Investigating the shortcomings of HMM synthesis

This paper presents the beginnings of a framework for formal testing of the causes of the current limited quality of HMM (Hidden Markov Model) speech synthesis. This framework separates each of the effects of modelling to observe their independent effects on vocoded speech parameters in order to address the issues that are restricting the progression to highly intelligible and natural-sounding speech synthesis. The simulated HMM synthesis conditions are performed on spectral speech parameters and tested via a pairwise listening test, asking listeners to perform a “same or different ” judgement on the quality of the synthesised speech produced between these conditions. These responses are then processed using multidimensional scaling to identify the qualities in modelled speech that listeners are attending to and thus forms the basis of why they are distinguishable from natural speech. The future improvements to be made to the framework will finally be discussed which include the extension to more of the parameters modelled during speech synthesis

Virtual Reality Physics Scenarios

Many students taking physics early on in their education find that it may be difficult to associate the theory they learn in class with how physics works in real world scenarios. Through various experiments in class, students are able to see examples of physics phenomena, but those experiments are limited by equipment, and do not offer precise data. To combat this, we are creating a virtual reality application for students to use to help learn physics. This report details the requirements the system will meet, as well as the use cases and subsequent activity diagrams for all users. We have also included a conceptual model of our system, as well as an explanation for technologies used, and a test plan and development timeline

Taming the waterways: The Europeanization of Southern Québec's riverside landscapes during the 16th–18th centuries

The arrival of Europeans in the New World effected the interaction of 2 temperate biogeographical eco-zones: the Palaearctic and Nearctic. Alfred Crosby has hypothesized that the success of the Europeans as imperialists was due, in part, to the ability of their introduced biota to bring about the collapse of the indigenous populations and local ecosystems, leading to the formation of Neo-European eco-spaces. Through a comparison of paleontological and environmental archaeological data from southern Québec, Canada, we examined Crosby's ecological imperialism model and assessed the biological impact of colonialism on the physical landscape during the 16th to early 18th centuries. The Intendant's Palace site in Québec City is employed as a case study and diachronically contextualized with data from contemporaneous sites in the region. The Europeanization of the landscape as a result of settlement construction, subsistence, and commodification was evidenced through signs of deforestation as well as the arrival of socioeconomic taxa. The biological transfer of European species did not appear to herald the collapse of local ecosystems but rather the establishment of an ecological melting pot along the early colonial waterways of southern Québec

Lepton Mixing Predictions including Majorana Phases from Δ(6n2)\Delta(6n^2) Flavour Symmetry and Generalised CP

Generalised CP transformations are the only known framework which allows to predict Majorana phases in a flavour model purely from symmetry. For the first time generalised CP transformations are investigated for an infinite series of finite groups, $\Delta(6n^2)=(Z_n\times Z_n)\rtimes S_3$. In direct models the mixing angles and Dirac CP phase are solely predicted from symmetry. $\Delta(6n^2)$ flavour symmetry provides many examples of viable predictions for mixing angles. For all groups the mixing matrix has a trimaximal middle column and the Dirac CP phase is 0 or $\pi$. The Majorana phases are predicted from residual flavour and CP symmetries where $\alpha_{21}$ can take several discrete values for each $n$ and the Majorana phase $\alpha_{31}$ is a multiple of $\pi$. We discuss constraints on the groups and CP transformations from measurements of the neutrino mixing angles and from neutrinoless double-beta decay and find that predictions for mixing angles and all phases are accessible to experiments in the near future.Comment: 16 pages, 8 figures; references added; clarification in section 2.3 added; results are unchange

Designing scattering-free isotropic index profiles using phase-amplitude equations

The Helmholtz equation can be written as coupled equations for the amplitude and phase. By considering spatial phase distributions corresponding to reflectionless wave propagation in the plane and solving for the amplitude in terms of this phase, we designed two-dimensional graded-index media which do not scatter light. We give two illustrative examples, the first of which is a periodic grating for which diffraction is completely suppressed at a single frequency at normal incidence to the periodicity. The second example is a medium which behaves as a 'beam shifter' at a single frequency; acting to laterally shift a plane wave, or sufficiently wide beam, without reflection.Comment: 10 pages, 10 figure

Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential

A

Dynamic muscle quality of the plantar flexors is impaired in claudicant patients with peripheral arterial disease and associated with poorer walking endurance

Objective Peripheral arterial disease and intermittent claudication (PAD-IC) negatively affects physical activity and function. There is evidence for plantarflexor muscle dysfunction and weakness; however, the extent to which this dysfunction can be attributed to reduced muscle size or quality, or both, is not yet known. This study investigated whether in vivo plantarflexor muscle quality during static and dynamic contractions is altered by PAD-IC and whether such changes are associated with impaired walking endurance according to initial and absolute claudication distances. Methods The study recruited 22 participants, consisting of 10 healthy controls and 12 claudicant patients with occlusion of the superficial femoral artery (seven unilateral and five bilateral). Muscle quality of the combined gastrocnemius muscles during static contractions was calculated by normalizing the estimated maximal potential muscle force to the physiological cross-sectional area of the lateral and medial gastrocnemius. Muscle quality during dynamic contractions of the combined plantarflexor muscles was calculated as the ratio of peak voluntary concentric plantarflexor power and the summed volume of lateral and medial gastrocnemius. Results Dynamic muscle quality was 24% lower in the claudicating-limb and asymptomatic-limb groups compared with controls (P = .017 and P = .023). The differences were most apparent at the highest contraction velocity (180°/s). Dynamic muscle quality was associated with reduced walking endurance (R = 0.689, P = .006 and R = 0.550, P = .042 for initial and absolute claudication distance, respectively). The claudicating-limb group demonstrated a trend toward reduced static muscle quality compared with controls (22%, P = .084). The relative contribution of the soleus muscle to plantarflexion maximum voluntary contraction was significantly higher in the claudicating-limb and asymptomatic-limb groups than in controls (P = .012 and P = .018). Conclusions The muscle strength of the plantarflexors in those with PAD-IC appears to be impaired at high contraction velocities. This may be explained by some reduction in gastrocnemii muscle quality and a greater reliance on the prominently type I-fibered soleus muscle. The reduced dynamic capability of the plantarflexor muscles was associated with disease severity and walking ability; therefore, efforts to improve plantarflexor power through dynamic exercise intervention are vital to maintain functional performance